CHROMOSOMAL INSTABILITY ASSOCIATED WITH ADVERSE OUTCOME: A CASE REPORT OF PATIENT WITH NIJMEGEN BREAKAGE SYNDROME AND RAPIDLY DEVELOPED T-NHL WITH COMPLEX KARYOTYPE

Chromosomal instability associated with adverse outcome: a case report of patient with Nijmegen breakage syndrome and rapidly developed T-NHL with complex karyotype

Abstract Background Nijmegen breakage syndrome (NBS) is a rare genetic disorder inherited in an autosomal recessive pattern associated with an increased risk of developing lymphoproliferative disorders, mainly non-Hodgkin lymphoma (NHL) and acute lymphoblastic leukemia (ALL).NBS patients are 50 times more likely to develop malignancy than healthy c

read more



Changing landscape configuration demands ecological planning: Retrospect and prospect for megaherbivores of North Bengal.

The Gorumara National Park (GNP) is an important conservation area located in the northern region of West Bengal State, India, as it provides habitat for three megaherbivores: Indian One-horned rhinoceros (Rhinoceros unicornis), Asian elephants (Elephas maximus) and Gaurs (Bos gaurus).It harbours one of the last population of the one-horned rhino.I

read more